Description
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55.
Product
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Molecular Weight
Calculated MW: 44 kDa; Observed MW: 44 kDa
Swiss-Prot
Q99816
Purification & Purity
The antibody was purified by immunogen affinity chromatography.
Applications
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
DATA
Immunocytochemistry analysis of TSG101 in HT-1080 using TSG101 antibody, and DAPI.
Storage & Stability
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note
For research use only, not for use in diagnostic procedure.